The Brown Cancer Center was the first in the Kentuckiana region to receive a three-year accreditation for the American Society for Therapeutic Radiology and Oncology (ASTRO) and American College of Radiology (ACR).

Radiation Oncologists are an integral part of multidisciplinary cancer teams at Brown Cancer Center who come together to develop tailored treatment plans for each cancer patient based on type of cancer, stage, lifestyle needs and overall health.

Diseases and Conditions

  • Benign diseases
  • Brain cancer
  • Breast cancer
  • General urologic cancers
  • Gastrointestinal cancers
  • Gynecologic cancers
  • Head and neck cancers
  • Lung cancer
  • Lymphoma
  • Metastatic disease
  • Ocular tumors
  • Orbital tumors
  • Pediatric cancers
  • Sarcoma
  • Skin cancer

Treatments and Services

Radiation oncology patients are seen and treated within UofL Health - Brown Cancer Center. Brown Cancer Center is the first facility in Kentucky to offer the TrueBeam System by Varian, and the first center in Louisville to offer CyberKnife, the world’s first and only robotic radiosurgery system for the body. With the state-of-the-art equipment available at Brown Cancer Center, we are the regional leader in many radiation oncology technology platforms including:

  • CyberKnife
  • TrueBeam
  • Trilogy
  • TomoTherapy
  • Brachytherapy

Radiation oncology is an integral part of multidisciplinary cancer teams at Brown Cancer Center that come together to develop tailored treatment plans for each patient. Our patients benefit from the combined expertise of many physicians and staff from various specialties throughout UofL Health. This expertise includes the Brown Cancer Center radiotherapy team, which consists of physicians, nurses, therapists, dosimetrists, physicists, a social worker, a dietitian and a chaplain, all specifically trained to meet the needs of cancer patients and their families.


For decades, cancer treatment often came with debilitating side effects and took several weeks or months to complete. Breakthrough technology such as CyberKnife has given hope to patients who seek alternatives to radiation therapy.

CyberKnife is an advanced technology that delivers a specialized form of radiation therapy called stereotactic radiosurgery, or stereotactic body radiation therapy (SRS).

SRS is a highly precise form of radiation therapy initially used to treat brain tumors and abnormalities, but used for multiple cancer treatments today. Despite its name, SRS is a non-surgical procedure that delivers precisely-targeted radiation at much higher doses than traditional radiation therapy while sparing healthy tissue nearby.

CyberKnife is comprised of a compact linear accelerator, a machine that generates a radiation beam, attached to a highly maneuverable robotic arm. It features a device that controls the width of the radiation beams the machine delivers during treatment, allowing our clinical experts to vary the beam size and treat a larger variety of tumors throughout the body.

During CyberKnife procedures, patients will lie on a treatment table while the machine’s robotic arm moves around their body delivering high doses of radiation directly to their tumor with pinpoint precision. The cumulative dose of radiation delivered by the CyberKnife kills tumor cells while minimizing exposure to surrounding healthy tissue.

Most treatment sessions typically last 30 to 90 minutes depending on the size, shape and location of your tumor.


The TrueBeam ™ system is an advanced radiotherapy system from Varian Medical Systems. It was engineered from the ground up to deliver more powerful cancer treatments with pinpoint accuracy and precision. It uniquely integrates advanced imaging and motion management technologies within a sophisticated new architecture that makes it possible to deliver treatments more quickly while monitoring and compensating for tumor motion, opening the door to new possibilities for the treatment of lung, breast, prostate, head and neck, as well as other cancers.


The Trilogy System is optimized for Intensity Modulated Radiation Therapy (IMRT) using Image Guided Radiation Therapy (IGRT).

  • Intensity Modulated Radiation Therapy is an advanced mode of high-precision radiotherapy that delivers precise radiation doses to a malignant tumor or specific areas within the tumor.
  • Image Guided Radiation Therapy is the use of frequent imaging during a course of radiation therapy to improve the precision and accuracy of the delivery of treatment.

The innovative RapidArc radiotherapy technology on a Trilogy system represents the latest evolution of cancer treatment technology, setting new benchmarks for speed, precision and patient comfort.

TomoTherapy Hi-Art System

Radiation Oncologists at Brown Cancer Center were the first in Kentucky to adopt the TomoTherapy System into clinical use. Its benefits include:

  • Delivery of therapeutic radiation from 360 degrees — Conventional machine design allows radiation to be delivered from only a few directions. More beam directions give physicians more control in how they plan treatments and more assurance that the dose will be confined to the tumor, reducing the risk of short and long-term side effects.
  • Thousands of targeted beamlets — The TomoTherapy treatment system uses a patented multi-leaf collimator (MLC) that divides the radiation beam into beamlets, all aimed at the tumor. Typically, tens of thousands of beamlets are used in a single TomoTherapy treatment session. Powerful software optimizes the contribution of each one to the total tumor dose, minimizing exposure to healthy tissue.


Brachytherapy consists of permanent radioactive “seeds”, or temporary radioactive catheters implanted into the cancerous tissue. An advantage of brachytherapy over traditional external beam radiation therapy is that higher doses of radiation can be safely delivered to the tissue with less radiation to the surrounding normal tissues.

Brown Cancer Center is the only facility in Kentucky using high dose rate brachytherapy for prostate cancer.

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