Clayton M. Smith, M.D., F.A.C.P.
Primary Care, Internal Medicine, Family Medicine
Areas of Interest
Gender-Affirming Care for Transgender/Non-Binary People | HIV Pre-Exposure Prophylaxis | Internal Medicine
Primary Practice Location
UofL Physicians – Primary Care
UofL Health – Chestnut Street Outpatient Center
401 East Chestnut Street, Suite 370
Louisville, KY 40202
502-588-4500 Get Directions
UofL Health – Chestnut Street Outpatient Center
401 East Chestnut Street, Suite 370
Louisville, KY 40202
502-588-4500 Get Directions
Get to know
Clayton M. Smith, M.D., F.A.C.P.
I am an Associate Professor of Medicine and Chief of the Division of General Internal Medicine, Palliative Medicine and Medical Education. I graduated from the University of Miami Miller School of Medicine in 2009 and completed residency training at the University of Louisville in 2012.Education & Training
B.A.
Tulane University | New Orleans | 2005
Tulane University | New Orleans | 2005
M.D.
University of Miami Miller School of Medicine | Miami | 2009
University of Miami Miller School of Medicine | Miami | 2009
Residency
University of Louisville School of Medicine | Internal Medicine |
Louisville | 2012
Internship
University of Louisville School of Medicine | Internal Medicine | Louisville | 2010
University of Louisville School of Medicine | Internal Medicine | Louisville | 2010
Title(s)
Chief, Division of General Internal Medicine, Palliative Medicine and Medical Education; Associate Residency Program Director, Advisory Dean
Languages
English
Areas of Interest
Gender-Affirming Care for Transgender/Non-Binary People | HIV Pre-Exposure Prophylaxis | Internal Medicine
Certifications
ABIM (2012, 2022)Practice, Specialty or Service
School of Medicine
Associate Professor
Department of Medicine
Awards
Alpha Omega Alpha (2009)
Outstanding Teaching Award (2011)
Outstanding Senior Resident (2012)
Excellence in Teaching Award (2014)
Fellowship in American College of Physicians (2014)
Golden Apple Teaching Award (2016)
Louisville Magazine "Top Docs" (2016, 2017, 2019)
LEO Magazine Readers' Choice - Top Doctor in Louisville (2019, 2021)
Philosophy
"We work collaboratively to create a welcoming environment for all of our patients. Everyone’s health care needs are different, and we work with our patients to create plans that fit their lifestyles."
UofL Health – Chestnut Street Outpatient CenterPatient Comments
Sep 17, 2024
5 out of 5
I love that I don't need to explain my LGBTQ+ lifestyle to my provider. It's so refreshing compared to where I grew up and I will always be thankful for Dr. Smith's care.
Sep 14, 2024
5 out of 5
Dr. Smith is extremely efficient, and I certainly appreciate that fact. I always have a good experience at this office.
Sep 9, 2024
5 out of 5
Dr. Smith is kind and attentive. He listens and gives good feedback. I like that he goes over all medications and asks questions about any changes.
Sep 5, 2024
5 out of 5
Dr. Clayton Smith is a great provider! I always feel like he actually listens to me and cares about my health. He takes the time to address any concerns I might have and doesn't ever make me feel like I'm being rushed out so the next patient can be seen.
Aug 24, 2024
5 out of 5
Dr. Smith is a gift!
Aug 11, 2024
5 out of 5
Dr. Smith and his office team are excellent; I would recommend this provider to any friend of family member.
Aug 8, 2024
4.8 out of 5
Dr. Smith was very thorough in his history taking on this first visit and I am grateful for his interest and actions so far.
Aug 4, 2024
5 out of 5
Dr. Smith is fantastic. Absolutely a delight to have, extremely trustworthy and helpful.
Aug 1, 2024
5 out of 5
I have been very pleased with Dr Smith and with this UofL practice. I believe I receive excellent care, and the office team seem to work well together.
Jul 26, 2024
5 out of 5
Dr. Smith is an excellent and thoughtful provider who always makes me feel like he genuinely cares about my needs.
Jul 20, 2024
5 out of 5
Dr. Smith is a knowledgeable and caring person. I am very lucky to have him as my doctor.
Jul 20, 2024
5 out of 5
I very much enjoy working with Dr. Clay Smith. If I have any concerns or questions, I text via MyChart and he responds quickly. We have an excellent relationship. It is positive and comfortable and healing.
Jul 14, 2024
5 out of 5
Dr. Smith is outstanding!
Jul 11, 2024
5 out of 5
Dr. Smith is a thorough, knowledgeable and compassionate doctor.
Jun 23, 2024
4.6 out of 5
I am apparently doing well with the expert guidance from Dr. Smith. Staying on therapy and contending with ordinary daily stressors is being met.
Jun 15, 2024
4.56 out of 5
I've never met a physician as personable, thorough and with the awesome bedside manner Dr. Clay Smith has. He is an amazing role model for what physicians should be like.
Jun 4, 2024
5 out of 5
Dr. Smith takes excellent care of me.
Feb 6, 2024
5 out of 5
I always appreciate Dr. Smith's thoroughness. Whenever I email him with questions, he is quick to respond.
Feb 4, 2024
5 out of 5
Dr. Clay Smith has the best bedside manner and personality of any physician I have seen or worked with. I have been in healthcare for twenty years and he is the most thorough physician I have ever seen.
Jan 31, 2024
5 out of 5
Dr. Smith has been the best primary care physician I have had. He is friendly and listens, but he is also efficient in the check-up time. The office team have also been friendly, and they seem to work together well. I have recommended this practice to a number of friends.
Jan 28, 2024
5 out of 5
Dr. Clayton Smith was very professional and answered all of my questions in ways that were easy to understand. Explained all of the medications I had questions about. I truly feel that I'm in better hands with him as my primary care physician and really appreciate how he went above and beyond.
Jan 28, 2024
5 out of 5
Dr Smith and his staff provide the best medical care I've ever received. They make me feel heard, and are always happy to discuss any concerns or questions I have. I cannot reccomend them enough, they are an perfect example of how healthcare should be handled.
Jan 25, 2024
5 out of 5
Dr. Smith is a knowledgeable, compassionate clinician; He is truly an asset.
Jan 15, 2024
5 out of 5
I feel I have as excellent communication and relationship with Clayton Smith as possible. He responds to any questions I might have on my chart quickly and completely. I feel we are completely on the same page regarding my health care. Personally, I feel it is my responsibility to actively care for myself and his input is valuable!
Jan 11, 2024
5 out of 5
The doctor (Clayton Smith) was very thorough and informative.
Jan 11, 2024
5 out of 5
Dr. Smith and staff are very helpful and kind.
Dec 17, 2023
5 out of 5
Super grateful Dr Smith was able to see me within an hour of when I called. He is an excellent physician and the staff and he took great care of me.
Dec 14, 2023
5 out of 5
Dr. Clayton Smith always takes enough time to thoroughly go through all my health issues.
Dec 5, 2023
5 out of 5
Dr Smith is a great physician that cares about his patient.
Nov 16, 2023
5 out of 5
Dr Smith is the best!
Nov 14, 2023
5 out of 5
Dr. Smith is compassionate, competent, and a good communicator. It is always a pleasure to visit with him.
Nov 12, 2023
5 out of 5
Dr. Smith is always very thorough, and I am confident in his judgment.
Nov 9, 2023
5 out of 5
Dr. Smith and his associates/support team are amazing! I recommend ULP/Dr Smith to all my friends.
Nov 7, 2023
4.56 out of 5
I truly appreciate how much Dr. Smith and his staff make me feel cared for and how attentive they are when I come to the office or request assistance through the MyChart.
Nov 7, 2023
5 out of 5
I really like Dr. Clayton Smith and look forward to working with him on my healthcare needs.
Nov 7, 2023
5 out of 5
Dr Smith is the best Doctor I have ever had. He is very thorough, professional, and always offers the best options for the patients. I have met other patients of his, and they all seem to feel the same way. He is young and full of energy.
Nov 4, 2023
5 out of 5
This visit, including my doctor and the office staff, was great.
Nov 3, 2023
3.2 out of 5
This doctor could use work on his bedside manner. Discussion was cold and technical
Nov 2, 2023
5 out of 5
As always excellent service with Dr. Smith and his staff.
Nov 1, 2023
5 out of 5
Dr. Smith is the best overall Doctor I have seen in the last 60 years. From the moment I walk in everything goes smoothly, all the people are happy and friendly, and they all know everything about me.
Oct 31, 2023
4.96 out of 5
Dr. Clay Smith is one of the very best doctors in the city of Louisville. I am confident that he provides me with the best possible health care solutions for my specific circumstances. His clinic/office is always so welcoming, and the staff always goes above and beyond to make sure that every visit is pleasant and comfortable. I actually enjoy going to see Dr. Smith and his staff!
Oct 24, 2023
5 out of 5
I am thankful Dr. Smith Is my doctor. I'm not sure It's possible for me to thank him enough for his care.
Oct 15, 2023
5 out of 5
Dr Smith is wonderfully appreciated!
Oct 14, 2023
5 out of 5
On a medical standpoint I think Dr Smith has taken very good care of my medical needs. And mental health care. Thank You........................
Oct 12, 2023
4.52 out of 5
The provider is a very good listener.
Oct 8, 2023
5 out of 5
Dr. Smith is always great. I feel very comfortable with him and am pleased with his care.
UofL Physicians participates in most major health plans in Kentucky. Coverage may vary by specialty. Coverage limitations are dependent on the terms of your personal health plan. This is not a guarantee that all services you receive will be covered by your health plan. Review your health plan provider directory and/or consult with your plan to confirm coverage.
