UofL Health Surgeons Are the First in Kentucky to Perform a Brain Tumor Procedure Using GammaTile Therapy

Louisville, KY – A UofL Health – Restorative Neuroscience team has become the first in Kentucky to offer GammaTile® Therapy, a novel approach to treating brain tumors. Neurosurgeon Brian Williams, M.D. and his team worked alongside radiation oncologist Shiao Woo, M.D., FACR and others, developing a plan for the safe removal of an aggressive brain tumor.  Thomas Shober underwent brain tumor resection with GammaTile Therapy on August 1 and is recovering well.

GammaTile Therapy is an FDA-cleared, Surgically Targeted Radiation Therapy (STaRT) that is designed to delay tumor regrowth for patients with brain tumors while protecting healthy brain tissue.

“This is just another example of our multidisciplinary approach to patient care. We knew we would have to think outside the box in order to attack the reoccurring and aggressive tumor around Mr. Shober’s brain,” said Brian Williams, M.D., UofL Health – Restorative Neuroscience. “Through our collaboration with GammaTile, our team was able to accomplish this first in Kentucky procedure, proof of our commitment to innovative treatment for our patients.”

Over 200,000 patients are diagnosed with an aggressive brain tumor in the U.S. each year.  Aggressive brain tumors tend to be resistant to current treatments and have a high likelihood of recurrence. GammaTile is FDA-cleared for patients with newly diagnosed malignant brain tumors and recurrent brain tumors, including gliomas, glioblastomas, meningiomas, and brain metastases.

The postage-stamp-sized GammaTile, which is embedded with small radiation sources, is implanted in the last five minutes of brain tumor removal surgery. The radiation immediately begins targeting tumor cells in the area where the tumor is most likely to recur. Over time and after the radiation has been delivered, the tile naturally resorbs. GammaTile Therapy is shown to improve local tumor control, which can extend a patient’s life.

“GammaTile is an efficient way of treating certain brain tumors because the tiles are placed against the tumor in the operating room immediately after the tumor is removed,” said Shiao Woo, M.D., UofL Health - Brown Cancer Center - Radiation Oncology. “We are pleased to bring this new standard of care to Kentucky for the first time.”

The previous standard of care for patients with operable brain tumors is the surgical removal of the tumor followed by adjuvant therapy, including radiation and chemotherapy.  Traditional radiation is delivered in as many as 30 treatments extending over a period of several weeks. This causes a substantial burden of treatment for patients and their caregivers alike. With GammaTile, patients receive treatment as they go about their daily lives. Additionally, GammaTile is a highly targeted therapy.  While a therapeutic dose is delivered to the area most likely to have a recurrence, healthy tissue is spared.  As a result, most patients avoid losing their hair during treatment.

“We are honored to be working with the brain tumor specialists at UofL Health to deploy GammaTile Therapy for the purpose of improving the lives of patients with brain tumors,” said Matt Likens, president and CEO of GT MedTech. “Patients deserve access to new treatments that can extend their lifespan while improving quality of life. We are excited to expand the availability of GammaTile Therapy to other leading brain tumor treatment centers across the U.S.”

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UofL Health

UofL Health is a fully integrated regional academic health system with eight hospitals, four medical centers, Brown Cancer Center, Eye Institute, nearly 200 physician practice locations, and more than 1,000 providers in Louisville and the surrounding counties, including southern Indiana. Additional access to UofL Health is provided through a partnership with Carroll County Memorial Hospital. With more than 13,000 team members – physicians, surgeons, nurses, pharmacists and other highly-skilled health care professionals, UofL Health is focused on one mission: to transform the health of communities we serve through compassionate, innovative, patient-centered care.

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